Adverse effects of corticosteroids inhalers

In vitro studies have demonstrated that a chloroform extract of khat leaves is cytotoxic in cultures of KB, , and XP2B1 mammalian cells. This cytotoxicity appears to be because of inhibition of de novo RNA synthesis affecting all the cell strains tested; KB cells possessed some resistance to the toxicity. 40 The tannins found in khat leaves have been shown to thicken the mucosa of the oropharynx and esophagus and also may be carcinogenic. 41 Oral cancers in certain regions of Saudi Arabia have been found to occur mainly among patients who had been chronic khat chewers. 42 Esophageal and gastric carcinoma have been attributed to khat chewing and water-pipe smoking in men and women in Yemen. 41 Khat-chewing men living in the area of the horn of Africa were studied and were found to have an increased risk of oral carcinoma, especially when accompanied by alcohol and tobacco consumption. 43

Adverse effects of corticosteroids inhalers

adverse effects of corticosteroids inhalers

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