Fortunately, correction of man boobs is relatively straightforward and very successful. The exact method of correction depends on the age of the sufferer, the volume of tissue that needs to be reduced and also the predominant tissue within the breast. In young men, firm, dense tissue tends to predominate and the breasts may need a combination of liposculpture and tissue excision. Later in life, the prominent breasts (or man boobs) tend to be mainly composed of fatty tissue and liposculpture may be sufficient to correct the problem. If there is excess of skin as well as breast tissue, open surgery may be required.
Individuals who have cirrhosis or chronic liver disease may develop gynecomastia for several reasons. Cirrhotics tend to have increased secretion of the androgenic hormone androstenedione from the adrenal glands, increased conversion of this hormone into various types of estrogen,  and increased levels of SHBG, which leads to decreased blood levels of free testosterone.  Approximately 10–40% of individuals with Graves' disease (a common form of hyperthyroidism ) experience gynecomastia.  Increased conversion of testosterone to estrogen by increased aromatase activity,  increased levels of SHBG and increased production of testosterone and estradiol by the testes due to elevated levels of LH cause the gynecomastia. Proper treatment of the hyperthyroidism can lead to the resolution of the gynecomastia.