Though you may already be aware of potential side effects from testosterone abuse (note I said abuse and not use), here they are again: lowered HDL-cholesterol levels (good cholesterol), testicular atrophy, reductions in sperm count, prostate enlargement, liver damage (primarily with oral steroids that have been modified with a 17-alkyl substitution), menstrual irregularities, suppression of endogenous hormone levels (like LH and T), development of palpable breast tissue in men (also known as gynecomastia), clitoral enlargement, and acne.
There are many signals that control catabolism. Most of the known signals are hormones and the molecules involved in metabolism itself. Endocrinologists have traditionally classified many of the hormones as anabolic or catabolic, depending on which part of metabolism they stimulate. The so-called classic catabolic hormones known since the early 20th century are cortisol , glucagon , and adrenaline (and other catecholamines ). In recent decades, many more hormones with at least some catabolic effects have been discovered, including cytokines , orexin (also known as hypocretin ), and melatonin . [ citation needed ]