Steroid dose conversion

I have just over 4 years of sobriety from a horrible alcohol and hydrocodone addiction. I started taking an anti depressant not long after sobriety because I was miserable. They helped a little, but I was still not myself. Last year was the first time I heard of Kratom and after weeks of research I started taking greens. Wow! I no longer need the prescriptions. Since then I have fully submitted my life to Jesus and things keep looking up for me. Praise God for giving us this wonderful plant! Genesis 1:29 “And God said, Behold, I have given you every herb bearing seed, which is upon the face of all the earth, and every tree, in the which is the fruit of a tree yielding seed: to you it shall be for food.”

Corticosteroids have been used as drug treatment for some time. Lewis Sarett of Merck & Co. was the first to synthesize cortisone, using a complicated 36-step process that started with deoxycholic acid, which was extracted from ox bile . [43] The low efficiency of converting deoxycholic acid into cortisone led to a cost of US $200 per gram. Russell Marker , at Syntex , discovered a much cheaper and more convenient starting material, diosgenin from wild Mexican yams . His conversion of diosgenin into progesterone by a four-step process now known as Marker degradation was an important step in mass production of all steroidal hormones, including cortisone and chemicals used in hormonal contraception . [44] In 1952, . Peterson and . Murray of Upjohn developed a process that used Rhizopus mold to oxidize progesterone into a compound that was readily converted to cortisone. [45] The ability to cheaply synthesize large quantities of cortisone from the diosgenin in yams resulted in a rapid drop in price to US $6 per gram, falling to $ per gram by 1980. Percy Julian's research also aided progress in the field. [46] The exact nature of cortisone's anti-inflammatory action remained a mystery for years after, however, until the leukocyte adhesion cascade and the role of phospholipase A2 in the production of prostaglandins and leukotrienes was fully understood in the early 1980s.

Dianabol is also capable of interaction with the enzyme aromatase resulting in the possibility of estrogenic side effects. Gynecomastia may become apparent even very early into a cycle, so the user must always ensure that they have the necessary drugs to treat the condition at the earliest possible opportunity. A Selective Estrogen Modulator (SERM) such as Tamoxifen (brand name Nolvadex) is usually used in these instances, perhaps with the addition of an anti-estrogen such as Proviron or Arimidex which will help hinder further estrogenic conversion. (For more information see the article Combating Oestrogens & Progesterone ).

pancreatitis / Delayed / 0-
toxic epidermal necrolysis / Delayed / 0-
exfoliative dermatitis / Delayed / 0-
erythema multiforme / Delayed / 0-
Stevens-Johnson syndrome / Delayed / 0-
AV block / Early / 0-
bradycardia / Rapid / 0-
vasculitis / Delayed / 0-
anaphylactoid reactions / Rapid / 0-
interstitial nephritis / Delayed / 0-
agranulocytosis / Delayed / 0-
hemolytic anemia / Delayed / Incidence not known
aplastic anemia / Delayed / Incidence not known
pancytopenia / Delayed / Incidence not known
atrophic gastritis / Delayed / Incidence not known

Steroid dose conversion

steroid dose conversion

pancreatitis / Delayed / 0-
toxic epidermal necrolysis / Delayed / 0-
exfoliative dermatitis / Delayed / 0-
erythema multiforme / Delayed / 0-
Stevens-Johnson syndrome / Delayed / 0-
AV block / Early / 0-
bradycardia / Rapid / 0-
vasculitis / Delayed / 0-
anaphylactoid reactions / Rapid / 0-
interstitial nephritis / Delayed / 0-
agranulocytosis / Delayed / 0-
hemolytic anemia / Delayed / Incidence not known
aplastic anemia / Delayed / Incidence not known
pancytopenia / Delayed / Incidence not known
atrophic gastritis / Delayed / Incidence not known

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